Tangential flow filtration (TFF) is a filtration technique where the medium is pumped parallel to the filter surface instead of directly through it. This minimises clogging and allows large volumes to be processed repeatedly without replacing the filter. TFF is a core technology in biopharma and downstream processing, where it is used for, among other things, concentrating, clarifying and buffer exchange of biological products such as proteins, antibodies and viruses. In single-use versions, TFF systems support full traceability and eliminate the risk of cross-contamination between product runs.